Molecular Dynamic (MD) Simulations Elucidates Putative Cu+-Transport Pathwa

Note: I highly recommend you read “Discovery of an Atomic Structure of Bacterial Cu+-Transport Protein Reveals Insight About Menkes/Wilson Disease” before this blog for clarification and background. In my previous blog, I talked about the solved atomic structure of Legionella pneumophilia CopA (LpCopA) and how the solved structure offered insight on the molecular pathway of … Read more

Discovery of an Atomic Structure of Bacterial Cu+-Transport Protein Reveals Insight About Menkes/Wilson Disease

Copper is an essential metal that we get from daily intake of foods and water. Without it, certain copper-dependent enzymes (“cuproenzymes”) cease to function which has negative consequences in energy production, brain and muscle development, and other biochemical/physiological processes in our bodies [1]. Menkes and Wilson are genetic conditions associated with deficient and toxic levels … Read more