Using CRISPR/Cas9 to correct a Wilson’s Disease Mutation in Human Cells
Wilson’s Disease (WD) is a liver disease caused by mutations in a protein responsible for copper excretion. That protein, ATPase7B (ATP7B), is a pump that helps move copper in liver cells, and mutations in it cause it to lose its ability to function. The impaired excretion of copper from the liver leads to the accumulation … Read more