Iron accumulation affects various proteins, such as Frataxin and Ceruloplasmin deficiency, triggering diseases such as Friedreich Ataxia and Aceruloplasminemia
Friedreich Ataxia (FRDA) and Aceruloplasminemia are both autosomal recessive disorders with severe impacts on the human body. They underscore the importance of metal homeostasis in the body, more specifically how crucial metals like iron and copper, although essential for numerous biological processes, can cause severe harm when misregulated. Friedreich Ataxia results from a genetic mutation … Read more