jdeluca

            Please refer to the first paragraph of the blog post titled “Mutations in the ECD of Zip4 lead to misfolding of Zip4 and acrodermatitis enteropathica (AE)” on the “Metals, Metalloproteins and Disease” blog for a description of acrodermatitis enteropathica (AE), its causes, its symptoms, and its traditional treatments.             In brief, this paper explores … Read more

            Acrodermatitis enteropathica (AE) is a disorder that results from zinc (Zn) deficiency in the cell. AE results from mutations in the SLC39A4 gene, which encode the Zip4 protein, a protein that brings Zn into the cytosol. It is most prevalent in babies, particularly when they are being weaned off breast milk. A second cause … Read more

            Epidermodysplasia verruciformis (EV) is a disease characterized by being more susceptible to β-Human Papillomaviruses (HPV), which is a strain of HPV. The primary clinical symptom is the formation of tons of wart-like lesions on patients. In one case, a man with EV had an operation to undergo the removal of 12 pounds (~5.5 kilos) … Read more