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Amyotrophic Lateral Sclerosis, or ALS, is a neurodegenerative disease primarily affecting the motor cortex and brain stem nuclei, leading to muscle atrophy, and sometimes language problems, behavioral changes and executive disfunction. Cytoskeletal defects leading to impaired neuronal transport, changes in RNA metabolism resulting in protein aggregates, impaired autophagy and mitochondrial dysfunction all serve as cellular … Read more

Alzheimer’s Disease is a neurodegenerative disease most commonly characterized through the formation of beta-amyloid (Aβ) plaques and the development of neurofibrillary tangles caused by the hyperphosphorylation of the tau protein. Both of these pathways ultimately result in the formation of protein aggregates that lead to the degeneration and loss of neurons. Zinc plays a role … Read more