Mutations in ZIP-ECD impairs zinc uptake into endosomal keratinocytes and causes Acrodermatitis Enteropathica

Zinc ions (Zn2+) are ingested through diet and can be found in a variety of foods – including the water supply. Zinc is the second most common transition metal ion found in the body (below iron) and is used as a cofactor in hundreds of proteins – including DNA-binding zinc-finger domains and carbonic anhydrase (converts … Read more